Publication

Exploring synergies between B- and T-cell vaccine approaches to optimize immune responses against HIV—workshop report

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Last modified
  • 01/14/2026
Type of Material
Authors
    Milton Maciel Jr., National Institutes of HealthRama R. Amara, Emory UniversityKatharine J. Bar, University of PennsylvaniaShane Crotty, La Jolla Institute for ImmunologySteven G. Deeks, University of California San FranciscoChristopher Duplessis, National Institutes of HealthGaurav Gaiha, Harvard Medical SchoolM. Juliana McElrath, Fred Hutchinson Cancer Research CenterAndrew McMichael, University of OxfordAmy Palin, National Institutes of HealthRachel Rutishauser, University of California San FranciscoStuart Shapiro, National Institutes of HealthStephen T. Smiley, National Institutes of HealthM. Patricia D'Souza, National Institutes of Health
Language
  • English
Date
  • 2024-02-21
Publisher
  • Nature Portfolio
Publication Version
Copyright Statement
  • © This is a U.S. Government work and not under copyright protection in the US; foreign copyright protection may apply 2024, corrected publication 2024
License
Final Published Version (URL)
Title of Journal or Parent Work
Volume
  • 9
Start Page
  • 39
Grant/Funding Agency
  • National Institutes of Health
Grant/Funding Information
  • This workshop was sponsored by the Division of AIDS (DAIDS), National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH).
Abstract
  • Correction to: npj Vaccines 10.1038/s41541-024-00818-y, published online 21 February 2024 In the original version of this Meeting Report, the incorrect statement “Out of nine HIV-1 vaccine efficacy trials completed so far, all but one demonstrated correlates of protection4” was inserted by mistake. The correct statement should have been “Out of nine HIV-1 vaccine efficacy trials completed so far, only one demonstrated correlates of protection4”. The correct statement is now shown in both the PDF and HTML versions of this Meeting Report.
  • The US National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institute of Health (NIH), convened a virtual workshop on August 8-9th, 2023 to explore potential synergies between HIV vaccine approaches that are designed to induce cellular or humoral immune responses. The goal of this workshop was to review data on leading vaccine candidates and to discuss the best strategies for combining these approaches to optimize immunity against HIV. Here, we summarize the findings reviewed at the workshop and discuss the knowledge gaps and priorities for future studies that will help accelerate the development of a preventive HIV vaccine.
Author Notes
  • The authors declare no competing interests.
  • Conceptualization: M.M.Jr., C.D., A.C.P., S.S., S.T.S., and M.P.D. Original writing: M.M.Jr., C.D., A.P., S.S., S.T.S., S.G.D., and M.P.D. Revisions: M.M.Jr., R.R.A., K.J.B., S.C., S.G.D., C.D., G.G., M.J.M., A.M., A.C.P., R.R., S.S., S.T.S., and M.P.D.
  • Correction published Mar. 14, 2024
  • We thank all workshop speakers and moderators for their discussion and insight. We thank Kristen Abboud for the draft manuscript.
Keywords
Research Categories
  • Immunology
  • Genetics

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