Ipsilateral cortical connections of dorsal and ventral premotor areas in New World owl monkeys

• Type of Material: Article
• Authors: Iwona Stepniewska, Vanderbilt University; Todd M Preuss, Emory University; Jon H. Kaas, Vanderbilt University
• Language: English
• Date: 2006-04-20
• Publisher: Wiley: 12 months
• Publication Version: Author Accepted Manuscript (After Peer Review)
• Copyright Statement: © 2006 Wiley-Liss, Inc.
• Final Published Version (URL): http://dx.doi.org/10.1002/cne.20906
• Title of Journal or Parent Work: Journal of Comparative Neurology
• ISSN: 0021-9967
• Volume: 495
• Issue: 6
• Start Page: 691
• End Page: 708
• Grant/Funding Information: NIH grant NS 16446
• Keywords: SOMATOSENSORY CORTEX; SOMATOTOPIC ORGANIZATION; CORTICOCORTICAL CONNECTIONS; Science & Technology; motor system; motor cortex; POSTERIOR PARIETAL CORTEX; Neurosciences & Neurology; STREPSIRHINE PRIMATE GALAGO; Zoology; posterior parietal cortex; INTRINSIC CONNECTIONS; Life Sciences & Biomedicine; GRANULAR FRONTAL-CORTEX; HORSERADISH-PEROXIDASE; PRIMARY MOTOR CORTEX; Neurosciences; MACAQUE MONKEY; primate evolution; primates
• Research Categories: Psychology, Psychobiology; Biology, Neuroscience

Abstract

In order to compare connections of premotor cortical areas of New World monkeys with those of Old World macaque monkeys and prosimian galagos, we placed injections of fluorescent tracers and wheat germ agglutinin-horseradish peroxidase (WGA-HRP) in dorsal (PMD) and ventral (PMV) premotor areas of owl monkeys. Motor areas and injection sites were defined by patterns of movements electrically evoked from the cortex with microelectrodes. Labeled neurons and axon terminals were located in brain sections cut either in the coronal plane or parallel to the surface of flattened cortex, and they related to architectonically and electrophysiologically defined cortical areas. Both the PMV and PMD had connections with the primary motor cortex (M1), the supplementary motor area (SMA), cingulate motor areas, somatosensory areas S2 and PV, and the posterior parietal cortex. Only the PMV had connections with somatosensory areas 3a, 1, 2, PR, and PV. The PMD received inputs from more caudal portions of the cortex of the lateral sulcus and more medial portions of the posterior parietal cortex than the PMV. The PMD and PMV were only weakly interconnected. New World owl monkeys, Old World macaque monkeys, and galagos share a number of PMV and PMD connections, suggesting preservation of a common sensorimotor network from early primates. Comparisons of PMD and PMV connectivity with the cortex of the lateral sulcus and posterior parietal cortex of owl monkeys, galagos, and macaques help identify areas that could be homologous.