Coronavirus Disease 2019 (COVID-19) Pandemic Implications in Pediatric and Adult Congenital Heart Disease

• Type of Material: Article
• Authors: Tarek Alsaied, University of Cincinnati; Jamil A. Aboulhosn, University of California Los Angeles; Timothy B. Cotts, University of Michigan; Curt J. Daniels, Ohio State University; Susan P. Etheridge, University of Utah; Timothy F. Feltes, Ohio State University; Michelle Z. Gurvitz, Boston Childrens Hospital; Mark B. Lewin, University of Washington; Matthew Oster, Emory University; Arwa Saidi, University of Florida
• Language: English
• Date: 2020-06-16
• Publisher: Wiley
• Publication Version: Author Accepted Manuscript (After Peer Review)
• Copyright Statement: © 2020 The Authors. Published on behalf of the American Heart Association, Inc., by Wiley Blackwell.
• License: Creative Commons Attribution-NonCommercial 4.0 International
• Final Published Version (URL): http://dx.doi.org/10.1161/JAHA.120.017224
• Title of Journal or Parent Work: Journal of the American Heart Association
• Volume: 9
• Issue: 12
• Start Page: 1
• End Page: 29
• Grant/Funding Information: None.
• Keywords: pediatric cardiology; adult congenital heart disease; Life Sciences & Biomedicine; Cardiovascular System & Cardiology; COVID-19; Science & Technology; Cardiac & Cardiovascular Systems; congenital heart disease
• Research Categories: Health Sciences, Medicine and Surgery; Health Sciences, Human Development; Health Sciences, Health Care Management

Abstract

The corona virus disease-2019 (COVID-19) is a recently described infectious disease caused by the severe acute respiratory syndrome corona virus 2 with significant cardiovascular implications. Given the increased risk for severe COVID-19 observed in adults with underlying cardiac involvement, there is concern that patients with pediatric and congenital heart disease (CHD) may likewise be at increased risk for severe infection. The cardiac manifestations of COVID-19 include myocarditis, arrhythmia and myocardial infarction. Importantly, the pandemic has stretched health care systems and many care team members are at risk for contracting and possibly transmitting the disease which may further impact the care of patients with cardiovascular disease. In this review, we describe the effects of COVID-19 in the pediatric and young adult population and review the cardiovascular involvement in COVID-19 focusing on implications for patients with congenital heart disease in particular.