Critical Illness Among Patients Hospitalized With Acute COVID-19 With and Without Congenital Heart Defects

• Type of Material: Article
• Authors: Karrie F Downing, Centers for Disease Control and Prevention COVID-19 Response Team, Atlanta; Regina M Simeone, Centers for Disease Control and Prevention COVID-19 Response Team, Atlanta; Matthew Oster, Emory University; Sherry L Farr, Centers for Disease Control and Prevention COVID-19 Response Team, Atlanta
• Language: English
• Date: 2022-04-12
• Publisher: LIPPINCOTT WILLIAMS & WILKINS
• Publication Version: Final Published Version
• Copyright Statement: © 2022 American Heart Association, Inc.
• Final Published Version (URL): http://dx.doi.org/10.1161/CIRCULATIONAHA.121.057833
• Title of Journal or Parent Work: CIRCULATION
• Volume: 145
• Issue: 15
• Start Page: 1182
• End Page: 1184
• Grant/Funding Information: None
• Keywords: heart defects; Peripheral Vascular Disease; Cardiovascular System & Cardiology; congenital; risk factors; Life Sciences & Biomedicine; Cardiac & Cardiovascular Systems; Science & Technology; COVID-19
• Research Categories: Health Sciences, Medicine and Surgery

Abstract

Given the increased risk for severe COVID-19 illness in individuals with cardiac disease, individuals with congenital heart defects (CHDs) might have increased risk of severe illness from COVID-19 as well.1 Most publications on CHD and COVID-19 illness have been restricted to patients at congenital cardiology centers, limiting generalizability, because many individuals with CHD do not receive specialized cardiology care.2–4 Furthermore, the studies did not include comparison groups without CHD or adjust for differences in established risk factors for critical COVID-19,4 and comparisons to general population estimates may be confounded.