Increased Antiviral Treatment Among Hospitalized Children and Adults With Laboratory-Confirmed Influenza, 2010-2015

• Type of Material: Article
• Authors: Grace D. Appiah, Epidemic Intelligence Service; Sandra S. Chaves, Centers for Disease Control and Prevention; Pam D. Kirley, California Emerging Infections Program; Lisa Miller, Colorado Department of Public Health and Environment; James Meek, Yale School of Public Health; Evan Anderson, Emory University; Oluwakemi Oni, Emory University; Patricia Ryan, Atlanta Veterans Affairs Medical Center; Seth Eckel, Iowa Department of Health; Ruth Lynfield, Maryland Department of Health and Mental Hygiene; Marisa Bargsten, Michigan Department of Health and Human Services; Shelley M. Zansky, Minnesota Department of Health; Nancy Bennett, New Mexico Department of Health; Krista Lung, New York State Department of Health; Christie McDonald-Hamm, University of Rochester; Ann Thomas, Ohio Department of Health; Diane Brady, Oklahoma Department of Health; Mary L. Lindegren, Oregon Department of Public Health; William Schaffner, Vanderbilt University; Mary Hill, Vanderbilt University; Shikha Garg, Centers for Disease Control and Prevention; Alicia M. Fry, Centers for Disease Control and Prevention; Angela Campbell, Emory University
• Language: English
• Date: 2017-02-01
• Publisher: Oxford University Press
• Publication Version: Author Accepted Manuscript (After Peer Review)
• Copyright Statement: © The Author 2016.
• Final Published Version (URL): http://dx.doi.org/10.1093/cid/ciw745
• Title of Journal or Parent Work: Clinical Infectious Diseases
• ISSN: 1058-4838
• Volume: 64
• Issue: 3
• Start Page: 364
• End Page: 367
• Grant/Funding Information: FluSurv-NET is a collaboration of state health departments, academic institutions, and local partners and is supported by the Centers for Disease Control and Prevention (cooperative agreements CDC-RFA-CK12-1202 and 5U38HM000414).
• Keywords: CHEMOPROPHYLAXIS; Microbiology; Infectious Diseases; antiviral; METAANALYSIS; INFECTION; influenza; NEURAMINIDASE INHIBITORS; Life Sciences & Biomedicine; Science & Technology; Immunology; oseltamivir
• Research Categories: Health Sciences, General; Health Sciences, Public Health

Abstract

Using population-based surveillance data, we analyzed antiviral treatment among hospitalized patients with laboratory-confirmed influenza. Treatment increased after the influenza A(H1N1) 2009 pandemic from 72% in 2010-2011 to 89% in 2014-2015 (P < .001). Overall, treatment was higher in adults (86%) than in children (72%); only 56% of cases received antivirals on the day of admission.