Factors associated with physical activity among adolescent and young adult survivors of early childhood cancer: A report from the childhood cancer survivor study (CCSS)

• Type of Material: Article
• Authors: Katie A. Devine, Rutgers Cancer Institute of New Jersey; Ann Mertens, Emory University; John A. Whitton, Fred Hutchinson Cancer Research Center; Carmen L. Wilson, St Jude Childrens Research Hospital; Kirsten K. Ness, St Jude Childrens Research Hospital; Jordan Marchak, Emory University; Wendy Leisenring, Fred Hutchinson Cancer Research Center; Kevin C. Oeffinger, Memorial Sloan Kettering Cancer Center; Leslie L. Robison, St Jude Childrens Research Hospital; Gregory T. Armstrong, St Jude Childrens Research Hospital; Kevin R. Krull, St Jude Childrens Research Hospital
• Language: English
• Date: 2018-02-01
• Publisher: WILEY
• Publication Version: Author Accepted Manuscript (After Peer Review)
• Copyright Statement: © 2017 John Wiley & Sons, Ltd.
• Final Published Version (URL): http://dx.doi.org/10.1002/pon.4528
• Title of Journal or Parent Work: Psycho-Oncology
• Volume: 27
• Issue: 2
• Start Page: 613
• End Page: 619
• Grant/Funding Information: Support also provided by the American Lebanese-Syrian Associated Charities (ALSAC).; This work was supported by the National Cancer Institute (CA55727).; Support to St. Jude Children’s Research Hospital also provided by the Cancer Center Support (CORE) grant (CA21765) and by ACS Grant RSG-01-021-01-CCE (A. Mertens, PI).
• Keywords: RISK-FACTORS; ACUTE LYMPHOBLASTIC-LEUKEMIA; Social Sciences; Biomedical Social Sciences; WELL; Social Sciences, Biomedical; HEALTH-STATUS; childhood cancer; LATE MORTALITY; Life Sciences & Biomedicine; psychological functioning; Science & Technology; Psychology, Multidisciplinary; EXERCISE; METAANALYSIS; Psychology; CARDIOVASCULAR EVENTS; survivors; Oncology; CHILDREN; 5-YEAR SURVIVORS; physical activity
• Research Categories: Psychology, Behavioral; Health Sciences, Oncology

Abstract

Objective: To evaluate concurrent and longitudinal associations between psychosocial functioning and physical activity in adolescent and young adult survivors of early childhood cancer. Methods: Adolescent survivors of early childhood cancer (diagnosed before age four) participating in the Childhood Cancer Survivor Study completed the Coping Health and Illness Profile–Adolescent Edition (CHIP-AE; n = 303; mean age at survey: 17.6 years). A subset of these survivors (n = 248) completed a follow-up survey an average of 6.0 years later (range: 4-10). Logistic regression identified associations between psychosocial functioning in adolescence and physical activity levels in adolescence and young adulthood. Results: Survivors reported low physical activity as adolescents (46.1% scored below CHIP-AE cut-point) and young adults (40.8% below Centers for Disease Control guidelines). Poor physical activity during adolescence was associated with female sex (OR = 2.06, 95% CI, 1.18-3.68), parents with less than a college education (OR = 1.91, 95% CI, 1.11-3.32), previous treatment with cranial radiation (OR = 3.35, 95% CI, 1.69-6.88), TV time (OR = 1.77, 95% CI, 1.00-3.14), and limitations of activity due to health or mobility restrictions (OR = 8.28, 95% CI, 2.87-30.34). Poor diet (OR = 1.84, 95% CI, 1.05-3.26) and low self-esteem (OR = 1.80, 95% CI, 0.99-3.31) during adolescence were associated with lower odds of meeting Centers for Disease Control physical activity guidelines in young adulthood. Conclusion: These findings provide targets for future interventional studies to improve physical activity in this high-risk population.