The genomic psychiatry cohort: Partners in discovery

• Type of Material: Article
• Authors: Michele T. Pato, University of Southern California; Janet L. Sobell, University of Southern California; Helena Medeiros, University of Southern California; Colony Abbott, University of Southern California; Brooke Sklar, University of Southern California; Peter F. Buckley, Georgia Regents University; Evelyn J. Bromet, State University of New York; Michael A. Escamilla, Texas Tech University; Ayman H. Fanous, Veterans Administration Medical Center, Washington; Douglas S. Lehrer, Wright State University; Fabio Macciardi, University of California Irvine; Dolores Malaspina, New York University; Steve A. McCarroll, Broad Institute of MIT and Harvard; Stephen R. Marder, University of California Los Angeles; Jennifer Moran, Broad Institute of MIT and Harvard; Christopher P. Morley, State University of New York; Humberto Nicolini, Carracci Medical Group, Mexico City; Diana O. Perkins, University of North Carolina; Becky Kinkead, Emory University; Mark Rapaport, Emory University
• Language: English
• Date: 2013-06-01
• Publisher: Wiley: 12 months
• Publication Version: Author Accepted Manuscript (After Peer Review)
• Copyright Statement: © 2013 Wiley Periodicals, Inc.
• Final Published Version (URL): http://dx.doi.org/10.1002/ajmg.b.32160
• Title of Journal or Parent Work: American Journal of Medical Genetics Part B: Neuropsychiatric Genetics
• ISSN: 1552-4841
• Volume: 162B
• Issue: 4
• Start Page: 306
• End Page: 312
• Grant/Funding Information: This project has been funded by NIH grants MH085548 and MH085542 and the Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard.
• Keywords: FEATURES; Psychiatry; genetic epidemiology; RELIABILITY; BIPOLAR-DISORDER; WIDE ASSOCIATION; LINKAGE; DIAGNOSTIC INTERVIEW; Science & Technology; Genetics & Heredity; SCHIZOPHRENIA; Life Sciences & Biomedicine; schizophrenia; repository; SCAN; bipolar disorder; COMMON VARIANTS; LOCUS
• Research Categories: Health Sciences, Public Health; Biology, Genetics; Health Sciences, Medicine and Surgery

Abstract

The Genomic Psychiatry Cohort (GPC) is a longitudinal resource designed to provide the necessary population-based sample for large-scale genomic studies, studies focusing on Research Domain Criteria (RDoC) and/or other alternate phenotype constructs, clinical and interventional studies, nested case-control studies, long-term disease course studies, and genomic variant-to-phenotype studies. We provide and will continue to encourage access to the GPC as an international resource. DNA and other biological samples and diagnostic data are available through the National Institute of Mental Health (NIMH) Repository. After appropriate review and approval by an advisory board, investigators are able to collaborate in, propose, and co-lead studies involving cohort participants.