Nups Take Leave of the nuclear envelope to regulate transcription

• Type of Material: Article
• Authors: Chunhui Hou, Emory University; Victor Corces, Emory University
• Language: English
• Date: 2010-02-05
• Publisher: Elsevier (Cell Press): 12 month embargo
• Publication Version: Author Accepted Manuscript (After Peer Review)
• Copyright Statement: ©2010 Elsevier Inc.
• License: Creative Commons Attribution-NonCommerical-NoDerivs 3.0 Unported
• Final Published Version (URL): http://dx.doi.org/10.1016/j.cell.2010.01.036
• Title of Journal or Parent Work: Cell
• ISSN: 0092-8674
• Volume: 140
• Issue: 3
• Start Page: 306
• End Page: 308
• Keywords: Nucleoporins; nuclear envelope; transcription; chromatin
• Research Categories: Biology, Cell; Biology, Genetics

Abstract

Although components of the nuclear pore complex have been implicated in gene regulation independent of their role at the nuclear envelope, the evidence so far has been indirect. Capelson et al. (2010) and Kalverda et al. (2010) now reveal that certain nucleoporins are actively involved in transcription inside the nucleoplasm of Drosophila cells.