Accelerating the Translation of Nanomaterials in Biomedicine

• Type of Material: Article
• Authors: Samir Mitragotri, University of California, Santa Barbara; Daniel G. Anderson, Massachusetts Institute of Technology; Xiaoyuan Chen, National University of Singapore; Edward K. Chow, Cancer Science Institute of Singapore; Dean Ho, The UCLA School of Dentistry; Alexander V. Kabanov, University of North Carolina at Chapel Hill; Jeffrey M. Karp, Harvard Medical School; Kazunori Kataoka, The University of Tokyo; Chad A. Mirkin, Northwestern University; Sarah Hurst Petrosko, Northwestern University; Jinjun Shi, Harvard Medical School; Molly M. Stevens, Imperial College London; Shouheng Sun, Brown University; Sweehin Teoh, Nanyang Technological University, Singapore; Subbu S. Venkatraman, Nanyang Technological University, Singapore; Younan Xia, Emory University; Shutao Wang, Chinese Academy of Sciences; Zhen Gu, University of North Carolina at Chapel Hill; Chenije Xu, Nanyang Technological University, Singapore
• Language: English
• Date: 2015-07-28
• Publisher: ACS Publications
• Publication Version: Author Accepted Manuscript (After Peer Review)
• Copyright Statement: © 2015 American Chemical Society.
• Final Published Version (URL): http://dx.doi.org/10.1021/acsnano.5b03569
• Title of Journal or Parent Work: ACS Nano
• Volume: 9
• Issue: 7
• Start Page: 6644
• End Page: 6654
• Grant/Funding Information: None declared
• Keywords: Nanomedicine; Nanomaterials; Translational Medical Research; Cancer therapy; Oncology; Nanoparticles; Drug delivery
• Research Categories: Engineering, Chemical; Chemistry, Biochemistry; Engineering, Biomedical; Health Sciences, Oncology

Abstract

Due to their size and tailorable physicochemical properties, nanomaterials are an emerging class of structures utilized in biomedical applications. There are now many prominent examples of nanomaterials being used to improve human health, in areas ranging from imaging and diagnostics to therapeutics and regenerative medicine. An overview of these examples reveals several common areas of synergy and future challenges. This Nano Focus discusses the current status and future potential of promising nanomaterials and their translation from the laboratory to the clinic, by highlighting a handful of successful examples.