Changing paradigms in Aedes control: considering the spatial heterogeneity of dengue transmission

• Type of Material: Article
• Authors: Veerle Vanlerberghe, Institute of Tropical Medicine; Hector Gomez-Dantes, Instituto Nacional de Salud Publica; Gonzalo Vazquez Prokopec, Emory University; Neal Alexander, London School of Hygiene and Tropical Medicine; Pablo Manrique-Saide, Emory University; Giovanini Coelho, Brazilian Ministry of Health; Maria Eugenia Toledo, Institute of Tropical Medicine; Clara B. Ocampo, International Training and Medical Research Center; Patrick Van der Stuyft, Ghent University
• Language: English
• Date: 2017-02-08
• Publisher: Organización Panamericana de la Salud
• Publication Version: Final Published Version
• Copyright Statement: World Health Organization
• License: Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International
• Final Published Version (URL): http://dx.doi.org/10.26633/RPSP.2017.16
• Title of Journal or Parent Work: REVISTA PANAMERICANA DE SALUD PUBLICA-PAN AMERICAN JOURNAL OF PUBLIC HEALTH
• Volume: 41
• Grant/Funding Information: The DENTARGET network received funding from the framework agreement between the Institute of Tropical Medicine (Antwerp) and the Belgian Directorate-General for Development Co-operation.
• Keywords: Peru; dengue; Belgium; Colombia; Cuba; epidemiology; Mexico; Brazil; Caribbean region; Latin America; Aedes; vector control
• Research Categories: Health Sciences, Epidemiology

Abstract

Current dengue vector control strategies, focusing on reactive implementation of insecticide-based interventions in response to clinically apparent disease manifestations, tend to be inefficient, short-lived, and unsustainable within the worldwide epidemiological scenario of virus epidemic recrudescence. As a result of a series of expert meetings and deliberations, a paradigm shift is occurring and a new strategy, using risk stratification at the city level in order to concentrate proactive, sustained efforts in areas at high risk for transmission, has emerged. In this article, the authors 1) outline this targeted, proactive intervention strategy, within the context of dengue epidemiology, the dynamics of its transmission, and current Aedes control strategies, and 2) provide support from published literature for the need to empirically test its impact on dengue transmission as well as on the size of disease outbreaks. As chikungunya and Zika viruses continue to expand their range, the need for a science-based, proactive approach for control of urban Aedes spp. mosquitoes will become a central focus of integrated disease management planning.