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An Exploration of Subgroups of Neuropsychiatric Symptoms in Mild Cognitive Impairment and Their Risks of Conversion to Dementia or Death

Authors:Jiayue Qiu, University of PennsylvaniaFelicia Goldstein, Emory UniversityJohn Hanfelt, Emory University

Date:2022

Publisher:ELSEVIER SCIENCE INC

Publication Version:Author Accepted Manuscript (After Peer Review)

License:Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International

Targeting both BDNF/TrkB pathway and delta-secretase for treating Alzheimer's disease

Authors:Jianming Liao, Emory UniversityChun Chen, Emory UniversityEun Hee Ahn, Emory UniversityXia Liu, Emory UniversityHua Li, Huazhong University of Science & TechnologyLaura E Edgington-Mitchell, University of MelbourneZhonghua Lu, Shenzhen Inst Adv TechnolShuping Ming, Hubei University of Chinese MedicineKeqiang Ye, Emory University

Date:2021

Publisher:PERGAMON-ELSEVIER SCIENCE LTD

Publication Version:Author Accepted Manuscript (After Peer Review)

License:Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International

Phosphorylation regulates arginine-rich RNA-binding protein solubility and oligomerization

Authors:Sean R Kundinger, Emory UniversityEric Dammer, Emory UniversityLuming Yin, Emory UniversityCheyenne Hurst, Emory UniversitySarah Shapley, Emory UniversityLingyan Ping, Emory UniversitySohail Khoshnevis, Emory UniversityHoma Ghalei, Emory UniversityDuc M Duong, Emory UniversityNicholas Seyfried, Emory University

Date:2021

Publisher:ELSEVIER

Publication Version:Final Published Version

License:Creative Commons Attribution 4.0 International

microRNA-425 loss mediates amyloid plaque microenvironment heterogeneity and promotes neurodegenerative pathologies

Authors:Yong-Bo Hu, Shanghai Jiao Tong UniversityYong-Fang Zhang, Shanghai Jiao Tong UniversityRu-Jing Ren, Shanghai Jiao Tong UniversityEric Dammer, Emory UniversityXin-Yi Xie, Shanghai Jiao Tong UniversityShi-Wu Chen, Shanghai Jiao Tong UniversityQiang Huang, Shanghai Jiao Tong UniversityWan-Ying Huang, Shanghai Jiao Tong UniversityRui Zhang, Shanghai Jiao Tong UniversityHong-Zhuan Chen, Shanghai University of Traditional Chinese MedicineHao Wang, Shanghai Jiao Tong UniversityGang Wang, Shanghai Jiao Tong University

Date:2021

Publisher:WILEY

Publication Version:Final Published Version

License:Creative Commons Attribution 4.0 International

A proteomic network approach resolves stage-specific molecular phenotypes in chronic traumatic encephalopathy

Authors:Laura Gutierrez-Quiceno, Emory UniversityEric Dammer, Emory UniversityAshlyn G Johnson, Emory UniversityJames A Webster, Emory UniversityRhythm Shah, Emory UniversityDuc Duong, Emory UniversityLuming Yin, Emory UniversityNicholas Seyfried, Emory UniversityVictor E Alvarez, Boston UniversityThor D Stein, Boston UniversityAnn C McKee, Boston UniversityChadwick Hales, Emory University

Date:2021

Publisher:BMC

Publication Version:Final Published Version

License:Creative Commons Attribution 4.0 International

Targeting Hsc70-based autophagy to eliminate amyloid beta oligomers

Authors:Juan Dou, Emory UniversityPeng Su, Department of Pharmacology and Chemical BiologyChongchong Xu, Emory UniversityZhexing Wen, Emory UniversityZixu Mao, Emory UniversityWenming Li, Emory University

Date:2020

Publisher:Academic Press Inc. Elsevier Science

Publication Version:Author Accepted Manuscript (After Peer Review)

License:Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International

Targeted Quantification of Detergent-Insoluble RNA-Binding Proteins in Human Brain Reveals Stage and Disease Specific Co-aggregation in Alzheimer's Disease

Authors:Qi Guo, Emory UniversityEric Dammer, Emory UniversityMaotian Zhou, Emory UniversitySean R. Kundinger, Emory UniversityMarla Gearing, Emory UniversityJames Lah, Emory UniversityAllan Levey, Emory UniversityJoshua M. Shulman, Baylor College of MedicineNicholas Seyfried, Emory University

Date:2021

Publisher:Frontiers Media SA

Publication Version:Final Published Version

License:Creative Commons Attribution 4.0 International

Asparagine endopeptidase (delta secretase), an enzyme implicated in Alzheimer's disease pathology, is an inhibitor of axon regeneration in peripheral nerves

Authors:Arthur English, Emory UniversityXia Liu, Emory UniversityOlivia C Mistretta, Emory UniversityPatricia Ward, Emory UniversityKeqiang Ye, Emory University

Date:2021

Publisher:SOC NEUROSCIENCE

Publication Version:Final Published Version

License:Creative Commons Attribution 4.0 International

Delta-secretase triggers Alzheimer's disease pathologies in wild-type hAPP/hMAPT double transgenic mice

Authors:Zhourui Wu, Emory UniversityXia Liu, Emory UniversityLiming Cheng, Emory UniversityKeqiang Ye, Emory University

Date:2020

Publisher:SPRINGERNATURE

Publication Version:Final Published Version

License:Creative Commons Attribution 4.0 International

Integrated proteomics reveals brain-based cerebrospinal fluid biomarkers in asymptomatic and symptomatic Alzheimer's disease

Authors:Lenora Higginbotham, Emory UniversityLingyan Ping, Emory UniversityEric Dammer, Emory UniversityDuc M. Duong, Emory UniversityMaotian Zhou, Emory UniversityMarla Gearing, Emory UniversityCheyenne Hurst, Emory UniversityJonathan Glass, Emory UniversityStewart Factor, Emory UniversityErik Johnson, Emory UniversityIhab Hajjar, Emory UniversityJames Lah, Emory UniversityAllan Levey, Emory UniversityNicholas Seyfried, Emory University

Date:2020

Publisher:AMER ASSOC ADVANCEMENT SCIENCE

Publication Version:Final Published Version

License:Creative Commons Attribution-NonCommercial 4.0 International

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