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DNTPASE ACTIVITY
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The ability of SAMHD1 to block HIV-1 but not SIV requires expression of MxB
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Host SAMHD1 protein restricts endogenous reverse transcription of HIV-1 in nondividing macrophages
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The SAMHD1-mediated block of LINE-1 retroelements is regulated by phosphorylation
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Dephosphorylation of the HIV-1 restriction factor SAMHD1 is mediated by PP2A-B55 alpha holoenzymes during mitotic exit
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A SAMHD1 mutation associated with Aicardi-Goutieres syndrome uncouples the ability of SAMHD1 to restrict HIV-1 from its ability to downmodulate type I interferon in humans
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Restrictive influence of SAMHD1 on Hepatitis B Virus life cycle
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Kim, Baek
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Diaz-Griffero, Felipe
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Shepard, Caitlin
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Brandariz-Nunez, Alberto
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Mahboubi, Bijan
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Martinez-Lopez, Alicia
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Schnellbaecher, Esther
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Schott, Kerstin
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Buffone, Cindy
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Coggings, Si Ana
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2018
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Human Mutation
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Mobile DNA
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Nature Communications
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Retrovirology
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Scientific Reports
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Virology
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Keyword
DNTPASE ACTIVITY
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Science & Technology
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ACID BINDING-PROTEIN
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INFECTION
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Life Sciences & Biomedicine
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SAMHD1
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AICARDI-GOUTIERES SYNDROME
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HIV-1
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NUCLEASE ACTIVITY
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Aicardi-Goutieres syndrome
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